Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gli1  GLI-Kruppel family member GLI1   (Synonyms: Zfp5, Zfp-5)
Results	Reference
1	J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118
1	J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119
1*	J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91
1	J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39
1	J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48
1*	J:150375 Cobourne MT, Xavier GM, Depew M, Hagan L, Sealby J, Webster Z, Sharpe PT, Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49
1	J:317276 Dittmann K, Wuelling M, Uhmann A, Dullin C, Hahn H, Schweyer S, Vortkamp A, Wienands J, Inactivation of patched1 in murine chondrocytes causes spinal fusion without inflammation. Arthritis Rheumatol. 2014 Apr;66(4):831-40
1	J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59
1	J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192
1	J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132
1	J:152851 Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Development. 2009 Aug;136(15):2535-43
1	J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7
1*	J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879
1	J:260962 Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, Essential roles of G9a in cell proliferation and differentiation during tooth development. Exp Cell Res. 2017 Aug 15;357(2):202-210
1*	J:160585 Kesper DA, Didt-Koziel L, Vortkamp A, Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26
1	J:155826 King P, Paul A, Laufer E, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21185-90
1	J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28
1	J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60
1	J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670
1	J:316483 Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML, Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Dev Dyn. 2021 Dec;250(12):1778-1795
1	J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82
1*	J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062
1	J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092
1	J:183783 Ortega MC, Cases O, Merchan P, Kozyraki R, Clemente D, de Castro F, Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia. 2012 May;60(6):851-66
1	J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41
1*	J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302
1	J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32
1	J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12
1	J:290878 Sun X, Are A, Annusver K, Sivan U, Jacob T, Dalessandri T, Joost S, Fullgrabe A, Gerling M, Kasper M, Coordinated hedgehog signaling induces new hair follicles in adult skin. Elife. 2020 Mar 17;9:e46756
1	J:324690 Wang H, Zheng C, Lu W, He T, Fan J, Wang C, Jie Q, Chan D, Cheah KSE, Yang L, Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened. Matrix Biol. 2022 Apr 23;
1*	J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53
1	J:320691 Yadav VK, Berger JM, Singh P, Nagarajan P, Karsenty G, Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. J Clin Invest. 2022 Feb 15;132(4):e153752